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Medial Prefrontal Administration of MK-801 Impairs T-maze Discrimination Reversal Learning in Weanling Rats

Several executive functions rely on the medial prefrontal cortex (mPFC) in the rat. Aspiration and neurotoxic lesions of the mPFC impair reversal learning in adult rats [1, 16, 34, 55]. Systemic administration of MK-801, an NMDA receptor antagonist, impairs T-maze reversal learning in weanling rats...

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Main Authors: Watson, Deborah J., Stanton, Mark E.
格式: Artigo
語言:Inglês
出版: 2009
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2766851/
https://ncbi.nlm.nih.gov/pubmed/19643149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbr.2009.07.026
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