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Forskolin Changes the Relationship between Cytosolic Ca(2+) and Contraction in Guinea Pig Ileum

This study was designed to clarify the mechanism of the inhibitory effect of forskolin on contraction, cytosolic Ca(2+) level ([Ca(2+)](i)), and Ca(2+) sensitivity in guinea pig ileum. Forskolin (0.1 nM~10 µM) inhibited high K(+) (25 mM and 40 mM)- or histamine (3 µM)-evoked contractions in a concen...

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Bibliographic Details
Main Authors: Han, Koon Hee, Cheon, Gap Jin, Yeon, Dong Soo, Kwon, Seong Chun
Format: Artigo
Language:Inglês
Published: The Korean Physiological Society and The Korean Society of Pharmacology 2009
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2766733/
https://ncbi.nlm.nih.gov/pubmed/19885036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4196/kjpp.2009.13.3.189
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