Heme Oxygenase-1 Induced by Aprotinin Inhibits Vascular Smooth Muscle Cell Proliferation Through Cell Cycle Arrest in Hypertensive Rats

Spontaneous hypertensive rats (SHR) are an established model of genetic hypertension. Vascular smooth muscle cells (VSMC) from SHR proliferate faster than those of control rats (Wistar-Kyoto rats; WKY). We tested the hypothesis that induction of heme oxygenase (HO)-1 induced by aprotinin inhibits VS...

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Detalhes bibliográficos
Main Authors: Choi, Hyoung Chul, Lee, Kwang Youn, Lee, Dong Hyup, Kang, Young Jin
Formato: Artigo
Idioma:Inglês
Publicado em: The Korean Physiological Society and The Korean Society of Pharmacology 2009
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2766711/
https://ncbi.nlm.nih.gov/pubmed/19885015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4196/kjpp.2009.13.4.309
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