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RhoB plays an essential role in CXCR2 sorting decisions

The CXCR2 chemokine receptor is a G-protein-coupled receptor that undergoes clathrin-mediated endocytosis upon ligand binding. The trafficking of CXCR2 is crucial for cells to maintain a proper chemotactic response. The mechanisms that regulate the recycling/degradation sorting decision are unknown....

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Bibliographic Details
Main Authors: Neel, Nicole F., Lapierre, Lynne A., Goldenring, James R., Richmond, Ann
Format: Artigo
Language:Inglês
Published: 2007
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2766565/
https://ncbi.nlm.nih.gov/pubmed/17405813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.03437
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