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Plant-derived human acetylcholinesterase-R provides protection from lethal organophosphate poisoning and its chronic aftermath

Therapeutically valuable proteins are often rare and/or unstable in their natural context, calling for production solutions in heterologous systems. A relevant example is that of the stress-induced, normally rare, and naturally unstable “read-through” human acetylcholinesterase variant, AChE-R. AChE...

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Detalhes bibliográficos
Main Authors: Evron, Tama, Geyer, Brian C., Cherni, Irene, Muralidharan, Mrinalini, Kilbourne, Jacquelyn, Fletcher, Samuel P., Soreq, Hermona, Mor, Tsafrir S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2766558/
https://ncbi.nlm.nih.gov/pubmed/17475919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.07-8112com
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