Absence of an interaction between the angiotensin converting enzyme (ACE) insertion-deletion polymorphism and pravastatin on cardiovascular disease in high-risk hypertensives: The GenHAT Study

BACKGROUND: The aim of this study was to determine whether the ACE insertion-deletion (I/D) polymorphism interacts with pravastatin to modify the risk of CHD and other cardiovascular endpoints in a large clinical trial. METHODS: GenHAT is an ancillary study of the Antihypertensive and Lipid Lowering...

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Main Authors: Maitland-van der Zee, Anke-Hilse, Boerwinkle, Eric, Arnett, Donna K., Davis, Barry R., Leiendecker-Foster, Catherine, Miller, Michael B., Klungel, Olaf H., Ford, Charles E., Eckfeldt, John H.
Format: Artigo
Jezik:Inglês
Izdano: 2007
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2766552/
https://ncbi.nlm.nih.gov/pubmed/17174637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ahj.2006.10.019
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