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Intranasal administration of IGF-1 attenuates hypoxic-ischemic brain injury in neonatal rats

To determine whether intranasal administration (iN) of recombinant human insulin-like growth factor-1 (rhIGF-1) provides neuroprotection to the neonatal rat brain following cerebral hypoxia-ischemia (HI), two doses of rhIGF-1 (50 μg at a 1 h interval) were infused into the right naris of postnatal d...

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Autori principali: Lin, Shuying, Fan, Lir-Wan, Rhodes, Philip G., Cai, Zhengwei
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2766530/
https://ncbi.nlm.nih.gov/pubmed/19332057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2009.03.021
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