Erythrocyte-Bound Tissue Plasminogen Activator is Neuroprotective in Experimental Traumatic Brain Injury

The purpose of this study was to test the effects of exogenous tissue plasminogen activator (tPA) in traumatic brain injury (TBI). We tested two different tPA formulations, free tPA and tPA bound to erythrocytes (RBC/tPA). Vehicle and each of the tPA treatments were injected intravenously into anest...

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Detalhes bibliográficos
Main Authors: Stein, Sherman C., Ganguly, Kumkum, Belfield, Caitlin M., Xu, Xiangsheng, Swanson, Edward W., Chen, Xiao-Han, Browne, Kevin D., Johnson, Victoria E., Smith, Douglas H., LeBold, David G., Cines, Douglas B., Muzykantov, Vladimir R.
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2009
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2766435/
https://ncbi.nlm.nih.gov/pubmed/19331516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/neu.2008.0720
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