Erythrocyte-Bound Tissue Plasminogen Activator is Neuroprotective in Experimental Traumatic Brain Injury

The purpose of this study was to test the effects of exogenous tissue plasminogen activator (tPA) in traumatic brain injury (TBI). We tested two different tPA formulations, free tPA and tPA bound to erythrocytes (RBC/tPA). Vehicle and each of the tPA treatments were injected intravenously into anest...

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Bibliographische Detailangaben
Hauptverfasser: Stein, Sherman C., Ganguly, Kumkum, Belfield, Caitlin M., Xu, Xiangsheng, Swanson, Edward W., Chen, Xiao-Han, Browne, Kevin D., Johnson, Victoria E., Smith, Douglas H., LeBold, David G., Cines, Douglas B., Muzykantov, Vladimir R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Mary Ann Liebert, Inc. 2009
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Original Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2766435/
https://ncbi.nlm.nih.gov/pubmed/19331516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/neu.2008.0720
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