Differential Activation of Guinea Pig Intrinsic Cardiac Neurons by the PAC1 Agonists Maxadilan and Pituitary Adenylate Cyclase-Activating Polypeptide 27 (PACAP27)

Pituitary adenylate cyclase-activating polypeptide (PACAP) evokes tachycardia followed by a larger cholinergic bradycardia in isolated guinea pig hearts. We used the selective PAC1 receptor agonist maxadilan and vasoactive intestinal polypeptide (VIP) to test the hypothesis that PACAP27-evoked tachy...

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Bibliographische Detailangaben
Hauptverfasser: Hoover, Donald B., Tompkins, John D., Parsons, Rodney L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The American Society for Pharmacology and Experimental Therapeutics 2009
Schlagworte:
Cardiovascular
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2766232/
https://ncbi.nlm.nih.gov/pubmed/19602551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.109.155747
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