A novel inhibitor of Chlamydophila pneumoniae protein kinase D (PknD) inhibits phosphorylation of CdsD and suppresses bacterial replication

BACKGROUND: We have shown previously that Chlamydophila pneumoniae contains a dual-specific Ser/Thr protein kinase that phosphorylates CdsD, a structural component of the type III secretion apparatus. To further study the role of PknD in growth and development we sought to identify a PknD inhibitor...

Full description

Saved in:
Bibliographic Details
Main Authors: Johnson, Dustin L, Stone, Chris B, Bulir, David C, Coombes, Brian K, Mahony, James B
Format: Artigo
Language:Inglês
Published: BioMed Central 2009
Subjects:
Research article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2765968/
https://ncbi.nlm.nih.gov/pubmed/19828035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2180-9-218
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items