The COMT Val158 Met polymorphism as an associated risk factor for Alzheimer disease and mild cognitive impairment in APOE 4 carriers

BACKGROUND: The aim of this study is to examine the influence of the catechol-O-methyltranferase (COMT) gene (polymorphism Val158 Met) as a risk factor for Alzheimer's disease (AD) and mild cognitive impairment of amnesic type (MCI), and its synergistic effect with the apolipoprotein E gene (AP...

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Detalhes bibliográficos
Main Authors: Martínez, Manuel Fernández, Martín, Xabier Elcoroaristizabal, Alcelay, Luís Galdos, Flores, Jessica Castro, Valiente, Juan María Uterga, Juanbeltz, Begoña Indakoetxea, Beldarraín, María Ángeles Gómez, López, Josefa Moraza, Gonzalez-Fernández, María Carmen, Salazar, Ana Molano, Gandarias, Rocio Bereincua, Borda, Sandra Inglés, Marqués, Nuria Ortiz, Amillano, Miryam Barandiarán, Zabaleta, María Carrasco, de Pancorbo, Marian M
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2009
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2765959/
https://ncbi.nlm.nih.gov/pubmed/19793392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2202-10-125
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