Profile of Native N-linked Glycan Structures from Human Serum Using High Performance Liquid Chromatography on a Microfluidic Chip and Time-of-Flight Mass Spectrometry

Protein glycosylation involves the addition of monosaccharides in a stepwise process requiring no glycan template. Therefore, identifying the numerous glycoforms, including isomers, can help elucidate the biological function(s) of particular glycans. A method to assess the diversity of the N-linked...

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Hauptverfasser: Chu, Caroline S., Niñonuevo, Milady R., Clowers, Brian H., Perkins, Patrick D., An, Hyun Joo, Yin, Hongfeng, Killeen, Kevin, Miyamoto, Suzanne, Grimm, Rudolf, Lebrilla, Carlito B.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2765869/
https://ncbi.nlm.nih.gov/pubmed/19288519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pmic.200800249
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