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Mandibular necrosis in beagle dogs treated with bisphosphonates
OBJECTIVES: To test the effect of bisphosphonate (BP) treatment for up to 3 years on bone necrosis and osteocyte death in the mandible using a canine model. MATERIALS AND METHODS: Dogs were treated with clinical doses of oral alendronate (ALN, 0.2 mg/kg/day or 1.0 mg/kg/day) for 1 or 3 years. In a s...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2765865/ https://ncbi.nlm.nih.gov/pubmed/19627524 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1601-6343.2009.01456.x |
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