Involvement of the Modifier Gene of a Human Mendelian Disorder in a Negative Selection Process

BACKGROUND: Identification of modifier genes and characterization of their effects represent major challenges in human genetics. SAA1 is one of the few modifiers identified in humans: this gene influences the risk of renal amyloidosis (RA) in patients with familial Mediterranean fever (FMF), a Mende...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Jéru, Isabelle, Hayrapetyan, Hasmik, Duquesnoy, Philippe, Cochet, Emmanuelle, Serre, Jean-Louis, Feingold, Josué, Grateau, Gilles, Sarkisian, Tamara, Jeanpierre, Marc, Amselem, Serge
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2009
Soggetti:
Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2765618/
https://ncbi.nlm.nih.gov/pubmed/19888326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0007676
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi