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Electronic and Steric Effects in Binding of Deep Cavitands

[Image: see text] A deep, self-folding cavitand responds to minor electronic differences between suitably sized adamantane guests. Binding constants range from <0.5 to 4000 M(-1) for guests as similar as 1-bromoadamantane and 1-cyanoadamantane. The barriers to guest exchange also vary up to 3 kca...

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Detalhes bibliográficos
Main Authors: Hooley, Richard J., Shenoy, Siddhartha R., Rebek, Julius
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2765558/
https://ncbi.nlm.nih.gov/pubmed/18989966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol8022775
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