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Intramolecular electron transfer in sulfite oxidizing enzymes: elucidating the role of a conserved active site arginine

All reported sulfite oxidizing enzymes have a conserved arginine in their active site which hydrogen bonds to the equatorial oxygen ligand on the Mo atom. Previous studies on the pathogenic R160Q mutant of human sulfite oxidase (HSO) have shown that Mo-heme intramolecular electron transfer (IET) is...

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Detalhes bibliográficos
Main Authors: Emesh, Safia, Rapson, Trevor D., Rajapakshe, S. Asha, Kappler, Ulrike, Bernhardt, Paul V., Tollin, Gordon, Enemark, John H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2765491/
https://ncbi.nlm.nih.gov/pubmed/19226119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi801553q
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