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Role of CYP1B1, MYOC, OPTN and OPTC genes in adult-onset primary open-angle glaucoma: predominance of CYP1B1 mutations in Indian patients

PURPOSE: Mutations in the CYP1B1, MYOC, OPTN, and WDR36 genes result in glaucoma. Given its expression in the optic nerve, it is likely a mutation in the OPTC gene is also involved in initiating glaucoma. This study was designed to evaluate the involvement of the CYP1B1, MYOC, OPTN, and OPTC genes i...

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Autori principali: Kumar, Arun, Basavaraj, Manjunath G., Gupta, Santosh K., Qamar, Imteyaz, Ali, Abdullah Mahmood, Bajaj, Vineeta, Ramesh, T.K., Prakash, D. Ravi, Shetty, Jyoti S., Dorairaj, Syril K.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Molecular Vision 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2765475/
https://ncbi.nlm.nih.gov/pubmed/17563717
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