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CIITA stimulation of transcription factor binding to major histocompatibility complex class II and associated promoters in vivo

CIITA is a master transactivator of the major histocompatibility complex class II genes, which are involved in antigen presentation. Defects in CIITA result in fatal immunodeficiencies. CIITA activation is also the control point for the induction of major histocompatibility complex class II and asso...

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Published in:Proc Natl Acad Sci U S A
Main Authors: Wright, Kenneth L., Chin, Keh-Chuang, Linhoff, Michael, Skinner, Cheryl, Brown, Jeffrey A., Boss, Jeremy M., Stark, George R., Ting, Jenny P.-Y.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 1998
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC27653/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9600954/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.11.6267
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