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Intestinal gaboxadol absorption via PAT1 (SLC36A1): modified absorption in vivo following co-administration of L-tryptophan

BACKGROUND AND PURPOSE: Gaboxadol has been in development for treatment of chronic pain and insomnia. The clinical use of gaboxadol has revealed that adverse effects seem related to peak serum concentrations. The aim of this study was to investigate the mechanism of intestinal absorption of gaboxado...

詳細記述

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書誌詳細
主要な著者: Larsen, M, Holm, R, Jensen, KG, Brodin, B, Nielsen, CU
フォーマット: Artigo
言語:Inglês
出版事項: Blackwell Publishing Ltd 2009
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2765307/
https://ncbi.nlm.nih.gov/pubmed/19594759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2009.00253.x
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