DETERMINATION OF ENDOCANNABINOID RECEPTOR ANTAGONIST SR141716 (RIMONABANT) IN PLASMA BY LIQUID CHROMATOGRAPH TANDEM MASS SPECTROMETRY

SR141716 (rimonabant) is an endocannabinoid receptor antagonist. Endocannabinoids are a class of chemicals that affect neurotransmission via G-protein coupled CB1 (brain) and CB2 (peripheral tissue) receptors. Numerous animal studies have shown that SR141716 binds with the CB1 receptor in the brain,...

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Autori principali: McCulloch, Melissa, Zhou, Xiang, Xu, Yan, Brunell, Steve, Spear, Linda
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2008
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2765253/
https://ncbi.nlm.nih.gov/pubmed/18258497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jchromb.2008.01.020
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