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The orexigenic hormone ghrelin defends against depressive symptoms of chronic stress
We found that increasing ghrelin levels, through subcutaneous injections or calorie restriction, produced anxiolytic- and antidepressant-like responses in the elevated plus maze and forced swim test. Moreover, chronic social defeat stress, a rodent model of depression, persistently increased ghrelin...
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| Main Authors: | , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2765052/ https://ncbi.nlm.nih.gov/pubmed/18552842 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn.2139 |
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