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Kinesin's step dissected with single-motor FRET

The motor protein Kinesin-1 drives intracellular transport along microtubules, with each of its two motor domains taking 16-nm steps in a hand-over-hand fashion. The way in which a single-motor domain moves during a step is unknown. Here, we use Förster resonance energy transfer (FRET) between fluor...

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Detalhes bibliográficos
Main Authors: Verbrugge, Sander, Lansky, Zdenek, Peterman, Erwin J. G.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2764935/
https://ncbi.nlm.nih.gov/pubmed/19805091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0905177106
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