SPFH1 and SPFH2 Mediate the Ubiquitination and Degradation of Inositol 1,4,5-Trisphosphate Receptors in Muscarinic Receptor-Expressing Hela Cells

Inositol 1,4,5-trisphosphate (IP(3)) receptors are endoplasmic reticulum (ER) membrane calcium channels that, upon activation, become substrates for the ER-associated degradation (ERAD) pathway. While it is clear that IP(3) receptors are polyubiquitinated and are transferred to the proteasome by a p...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Wang, Yuan, Pearce, Margaret M.P., Sliter, Danielle A., Olzmann, James A., Christianson, John C., Kopito, Ron R., Boeckmann, Stephanie, Gagen, Christine, Leichner, Gil S., Roitelman, Joseph, Wojcikiewicz, Richard J.H.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2009
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2764810/
https://ncbi.nlm.nih.gov/pubmed/19751772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamcr.2009.09.004
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