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Synthesis of cytochrome c oxidase subunit 1 is translationally downregulated in the absence of functional F(1)F(0)-ATP synthase

The mitochondrial F(1)F(0)-ATP synthase or ATPase is a key enzyme for aerobic energy production in eukaryotic cells. Mutations in ATPase structural and assembly genes are the primary cause of severe human encephalomyopathies, frequently associated with a pleiotropic decrease in cytochrome c oxidase...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Soto, Ileana C., Fontanesi, Flavia, Valledor, Melvys, Horn, Darryl, Singh, Rajiv, Barrientos, Antoni
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2764804/
https://ncbi.nlm.nih.gov/pubmed/19735676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamcr.2009.09.002
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