The Secreted Helicobacter Cysteine-rich Protein A Causes Adherence of Human Monocytes and Differentiation into a Macrophage-like Phenotype

H. pylori genomes typically contain 8 or 9 genes that code for secreted and highly disulfide-bridged proteins designated Helicobacter cysteine-rich proteins (Hcp). Here we show that HcpA (hp0211) but not HcpC (hp1098) triggers the differentiation of human myeloid Thp1 monocytes into macrophages. Sma...

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Detalhes bibliográficos
Main Authors: Dumrese, Claudia, Slomianka, Lutz, Ziegler, Urs, Choi, Sung Sook, Kalia, Awdhesh, Fulurija, Alma, Lu, Wei, Berg, Douglas E., Benghezal, Mohammed, Marshall, Barry, Mittl, Peer R.E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2764743/
https://ncbi.nlm.nih.gov/pubmed/19393649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2009.04.027
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