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Stage specificity, dose response, and doubling dose for mouse minisatellite germ-line mutation induced by acute radiation

Germ-line mutation induction at mouse minisatellite loci by acute irradiation with x-rays was studied at premeiotic and postmeiotic stages of spermatogenesis. An elevated paternal mutation rate was found after irradiation of premeiotic spermatogonia and stem cells, whereas the frequency of minisatel...

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Main Authors: Dubrova, Yuri E., Plumb, Mark, Brown, Julia, Fennelly, Jan, Bois, Philippe, Goodhead, Dudley, Jeffreys, Alec J.
Format: Artigo
Jezik:Inglês
Izdano: The National Academy of Sciences 1998
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC27647/
https://ncbi.nlm.nih.gov/pubmed/9600951
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