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Uremic cardiac hypertrophy is reversed by rapamycin but not by lowering of blood pressure

Chronic kidney disease is often complicated by uremic cardiomyopathy that consists of left ventricular hypertrophy and interstitial fibrosis. It is thought that hypertension and volume overload are major causes of this disease, but here we sought to identify additional mechanisms using a mouse model...

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Detalhes bibliográficos
Main Authors: Siedlecki, Andrew M., Jin, Xiaohua, Muslin, Anthony J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2764402/
https://ncbi.nlm.nih.gov/pubmed/19165175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ki.2008.690
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