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Protective Effect of Melatonin Against Mitomycin C-Induced Genotoxic Damage in Peripheral Blood of Rats

Mitomycin C (MMC) generates free radicals when metabolized. We investigated the effect of melatonin against MMC-induced genotoxicity in polychromatic erythrocytes and MMC-induced lipid peroxidation in brain and liver homogenates. Rats (N = 36) were classified into 4 groups: control, melatonin, MMC,...

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Detalhes bibliográficos
Main Authors: Ortega-Gutiérrez, S., López-Vicente, M., Lostalé, F., Fuentes-Broto, L., Martínez-Ballarín, E., García, J. J.
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2764378/
https://ncbi.nlm.nih.gov/pubmed/19859567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2009/791432
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