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Evaluation of 9-cis-Retinyl Acetate Therapy in Rpe65(−/−) Mice
PURPOSE: Mice lacking retinal pigment epithelium–specific 65-kDa protein (RPE65) develop retinopathy and blindness resembling Leber congenital amaurosis. Effects of 9-cis-retinyl acetate (9-cis-R-Ac) on visual function and retinopathy progression were tested in Rpe65(−/−) mice. METHODS: Young C57Bl/...
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| Main Authors: | , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2009
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2764364/ https://ncbi.nlm.nih.gov/pubmed/19407008 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.09-3700 |
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