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Large-Scale Sequence Analysis of M Gene of Influenza A Viruses from Different Species: Mechanisms for Emergence and Spread of Amantadine Resistance

Influenza A virus infects many species, and amantadine is used as an antiviral agent. Recently, a substantial increase in amantadine-resistant strains has been reported, most of which have a substitution at amino acid position 31 in the M2 gene. Understanding the mechanism responsible for the emerge...

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Detalhes bibliográficos
Main Authors: Furuse, Yuki, Suzuki, Akira, Oshitani, Hitoshi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2764202/
https://ncbi.nlm.nih.gov/pubmed/19651904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00650-09
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