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In Vitro Activity and In Vivo Efficacy of Clavulanic Acid against Acinetobacter baumannii

Clavulanic acid (CLA) exhibits low MICs against some Acinetobacter baumannii strains. The present study evaluates the efficacy of CLA in a murine model of A. baumannii pneumonia. For this purpose, two clinical strains, Ab11 and Ab51, were used; CLA MICs for these strains were 2 and 4 mg/liter, respe...

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Detalhes bibliográficos
Main Authors: Beceiro, Alejandro, López-Rojas, Rafael, Domínguez-Herrera, Juan, Docobo-Pérez, Fernando, Bou, Germán, Pachón, Jerónimo
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2764194/
https://ncbi.nlm.nih.gov/pubmed/19635957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00320-09
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