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New Variant of CTX-M-Type Extended-Spectrum β-Lactamases, CTX-M-71, with a Gly238Cys Substitution in a Klebsiella pneumoniae Isolate from Bulgaria

A single Klebsiella pneumoniae strain isolated in a Bulgarian hospital was found to produce CTX-M-71, a new CTX-M variant characterized by one amino acid substitution from glycine to cysteine at position 238 in comparison to CTX-M-15. This exchange decreased the hydrolytic activity of the β-lactamas...

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Detalhes bibliográficos
Main Authors: Schneider, Ines, Queenan, Anne Marie, Markovska, Rumyana, Markova, Boyka, Keuleyan, Emma, Bauernfeind, Adolf
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2764165/
https://ncbi.nlm.nih.gov/pubmed/19620330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00461-09
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