Antimalarial Activity of Simalikalactone E, a New Quassinoid from Quassia amara L. (Simaroubaceae)

We report the isolation and identification of a new quassinoid named simalikalactone E (SkE), extracted from a widely used Amazonian antimalarial remedy made out of Quassia amara L. (Simaroubaceae) leaves. This new molecule inhibited the growth of Plasmodium falciparum cultured in vitro by 50%, in t...

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Detaylı Bibliyografya
Asıl Yazarlar: Cachet, N., Hoakwie, F., Bertani, S., Bourdy, G., Deharo, E., Stien, D., Houel, E., Gornitzka, H., Fillaux, J., Chevalley, S., Valentin, A., Jullian, V.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology (ASM) 2009
Konular:
Experimental Therapeutics
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2764154/
https://ncbi.nlm.nih.gov/pubmed/19667291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00951-09
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