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Defining Coarse-Grained Representations of Large Biomolecules and Biomolecular Complexes from Elastic Network Models

Coarse-grained (CG) models of large biomolecular complexes enable simulations of these systems over long timescales that are not accessible for atomistic molecular dynamics (MD) simulations. A systematic methodology, called essential dynamics coarse-graining (ED-CG), has been developed for defining...

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Autors principals: Zhang, Zhiyong, Pfaendtner, Jim, Grafmüller, Andrea, Voth, Gregory A.
Format: Artigo
Idioma:Inglês
Publicat: The Biophysical Society 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2764101/
https://ncbi.nlm.nih.gov/pubmed/19843465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2009.08.007
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