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Adverse Childhood Events as Risk Factors for Substance Dependence: Partial Mediation by Mood and Anxiety Disorders

AIMS: Adverse childhood events (ACEs) are associated with negative health outcomes. We examined ACEs as risk factors for substance dependence (SD) and the mediating effects of mood and anxiety disorders on the relations between ACEs and SD risk. DESIGN: We compared early life experiences in 2,061 in...

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Detalhes bibliográficos
Main Authors: Douglas, Kara R., Chan, Grace, Gelernter, Joel, Arias, Albert J., Anton, Raymond F., Weiss, Roger D., Brady, Kathleen, Poling, James, Farrer, Lindsay, Kranzler, Henry R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2763992/
https://ncbi.nlm.nih.gov/pubmed/19720467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.addbeh.2009.07.004
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