IMAGING CORRELATES OF DIFFERENTIAL EXPRESSION OF INDOLEAMINE 2,3-DIOXYGENASE IN HUMAN BRAIN TUMORS

BACKGROUND: Tryptophan catabolism via the kynurenine pathway, mediated by indoleamine 2,3-dioxygenase (IDO), is a mechanism involved in tumor immuno-resistance. Positron emission tomography (PET) with α-[(11)C]methyl-L-tryptophan (AMT) can quantify transport and metabolism of tryptophan in infiltrat...

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Detaylı Bibliyografya
Asıl Yazarlar: Batista, Carlos E. A., Juhász, Csaba, Muzik, Otto, Kupsky, William J., Barger, Geoffrey, Chugani, Harry T., Mittal, Sandeep, Sood, Sandeep, Chakraborty, Pulak K., Chugani, Diane C.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2009
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2763988/
https://ncbi.nlm.nih.gov/pubmed/19434461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11307-009-0225-0
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