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Autophagy-dependent and -independent mechanisms of mitochondrial clearance during reticulocyte maturation

Erythrocyte formation involves the elimination of mitochondria at the reticulocyte stage of development. Nix(−/−) reticulocytes fail to eliminate their mitochondria at this step due to a defect in the targeting of mitochondria to autophagosomes. To determine the role of autophagy in this process, we...

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Detalhes bibliográficos
Main Authors: Zhang, Ji, Ney, Paul A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2763954/
https://ncbi.nlm.nih.gov/pubmed/19713771
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