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Retinoblastoma family protein promotes normal R8-photoreceptor differentiation in the absence of rhinoceros by inhibiting dE2F1 activity

The retinoblastoma gene Rb is a prototype tumor suppressor which is conserved in Drosophila. Although much is known about the roles of Rb in cell proliferation and apoptosis, much less is known about how Rb regulates cell differentiation. Inactivation of Drosophila Rb (rbf) exhibited subtle differen...

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Библиографические подробности
Главные авторы: Steele, Latishya, Sukhanova, Madina J., Xu, Jinhua, Gordon, Gabriel M., Huang, Yongsheng, Yu, Long, Du, Wei
Формат: Artigo
Язык:Inglês
Опубликовано: 2009
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2763947/
https://ncbi.nlm.nih.gov/pubmed/19744473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2009.09.004
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