A transcription-dependent increase in miniature EPSC frequency accompanies late-phase plasticity in cultured hippocampal neurons

BACKGROUND: The magnitude and longevity of synaptic activity-induced changes in synaptic efficacy is quantified by measuring evoked responses whose potentiation requires gene transcription to persist for more than 2-3 hours. While miniature EPSCs (mEPSCs) are also increased in amplitude and/or frequ...

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Main Authors: Wiegert, J Simon, Hofmann, Frank, Bading, Hilmar, Bengtson, C Peter
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2009
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2763873/
https://ncbi.nlm.nih.gov/pubmed/19788723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2202-10-124
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