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Impaired exercise tolerance and skeletal muscle myopathy in sulfonylurea receptor-2 mutant mice

By sensing intracellular energy levels, ATP-sensitive potassium (K(ATP)) channels help regulate vascular tone, glucose metabolism, and cardioprotection. SUR2 mutant mice lack full-length K(ATP) channels in striated and smooth muscle and display a complex phenotype of hypertension and coronary vasosp...

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Main Authors: Stoller, Douglas, Pytel, Peter, Katz, Sophie, Earley, Judy U., Collins, Keith, Metcalfe, Jamie, Lang, Roberto M., McNally, Elizabeth M.
Format: Artigo
Jezik:Inglês
Izdano: American Physiological Society 2009
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2763822/
https://ncbi.nlm.nih.gov/pubmed/19675276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.00081.2009
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