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Endotoxin depresses heart rate variability in mice: cytokine and steroid effects

Heart rate variability (HRV) falls in humans with sepsis, but the mechanism is not well understood. We utilized a mouse model of endotoxemia to test the hypothesis that cytokines play a role in abnormal HRV during sepsis. Adult male C57BL/6 mice underwent surgical implantation of probes to continuou...

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Bibliografiske detaljer
Main Authors: Fairchild, Karen D., Saucerman, Jeffrey J., Raynor, Laura L., Sivak, Joseph A., Xiao, Yuping, Lake, Douglas E., Moorman, J. Randall
Format: Artigo
Sprog:Inglês
Udgivet: American Physiological Society 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2763816/
https://ncbi.nlm.nih.gov/pubmed/19657103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.00132.2009
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