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The calcium-sensing receptor (CaSR) defends against hypercalcemia independently of its regulation of parathyroid hormone secretion

The calcium-sensing receptor (CaSR) controls parathyroid hormone (PTH) secretion, which, in turn, via direct and indirect actions on kidney, bone, and intestine, maintains a normal extracellular ionized calcium concentration (Ca(2+)(o)). There is less understanding of the CaSR's homeostatic imp...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Kantham, Lakshmi, Quinn, Steven J., Egbuna, Ogo I., Baxi, Khanjan, Butters, Robert, Pang, Jian L., Pollak, Martin R., Goltzman, David, Brown, Edward M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Physiological Society 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2763782/
https://ncbi.nlm.nih.gov/pubmed/19797241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00315.2009
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