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A Stable Isotope Method for the Simultaneous Measurement of Matrix Synthesis and Cell Proliferation in Articular Cartilage In Vivo

OBJECTIVE: Measurements of cell proliferation and matrix synthesis in cartilage explants have identified regulatory factors (e.g., interleukin 1, IL-1) that contribute to osteoarthritis and anabolic mediators (e.g., BMP-7) that may have therapeutic potential. The objective of this study was to devel...

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Detalhes bibliográficos
Main Authors: Li, Kelvin W., Siraj, Sebrin A., Cheng, Erika W., Awada, Mohamad, Hellerstein, Marc K., Turner, Scott M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2763636/
https://ncbi.nlm.nih.gov/pubmed/19230856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.joca.2009.01.006
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