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Design of a novel molecular beacon: modification of the stem with artificially genetic alphabet

A molecular beacon that incorporates components of an artificially expanded genetic information system (Aegis) in its stem is shown not to be opened by unwanted stem invasion by adventitious standard DNA; this should improve the “darkness” of the beacon in real-world applications.

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書目詳細資料
Main Authors: Sheng, Pinpin, Yang, Zunyi, Kim, Youngmi, Wu, Yanrong, Tan, Weihong, Benner, Steven A.
格式: Artigo
語言:Inglês
出版: 2008
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2763601/
https://ncbi.nlm.nih.gov/pubmed/18956044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/b811159f
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