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Accumulation of extracellular RGR-d in Bruch's membrane and close association with drusen at intercapillary regions

Human retinal pigment epithelial (RPE) cells synthesize an extraneous splice isoform of retinal G protein-coupled receptor (RGR). In this study, we analyzed the exon-skipping variant of RGR (RGR-d) that is found in extracellular deposits. RPE-choroid tissue sections were prepared from postmortem hum...

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Detalhes bibliográficos
Main Authors: Kochounian, Harold, Johnson, Lincoln V., Fong, Henry K. W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2763577/
https://ncbi.nlm.nih.gov/pubmed/19450444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exer.2009.01.019
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