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Casein Kinase I epsilon positively regulates the Akt pathway in breast cancer cell lines

The Akt pathway is very important in both development and cancer. Here we show that expression of Casein kinase I epsilon (CKIε) causes up-regulation of the Akt pathway despite normal protein expression of the pathway inhibitor Phosphata and tensin homologue deleted on chromosome ten (PTEN). Convers...

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Detalhes bibliográficos
Main Authors: Modak, Cristina, Bryant, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2763534/
https://ncbi.nlm.nih.gov/pubmed/18262492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2008.02.001
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