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α4(+)β7(hi)CD4(+) Memory T cells Harbor Most Th-17 cells and are Preferentially Infected During Acute SIV Infection

HIV/SIV are thought to infect minimally activated CD4(+) T cells after viral entry. Not much is known about why SIV selectively targets these cells. Here we show that CD4(+) T cells that express high levels of the α4β7 heterodimer are preferentially infected very early during the course of SIV infec...

詳細記述

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書誌詳細
主要な著者: Kader, Muhamuda, Wang, Xiaolei, Piatak, Michael, Lifson, Jeffrey, Roederer, Mario, Veazey, Ronald, Mattapallil, Joseph J.
フォーマット: Artigo
言語:Inglês
出版事項: 2009
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2763371/
https://ncbi.nlm.nih.gov/pubmed/19571800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mi.2009.90
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