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Highly Cooperative Recruitment of Ets-1 and Release of Autoinhibition by Pax5
Pax5 is a critical regulator of transcription and lineage commitment in B lymphocytes. In B cells, mb-1 (Ig-α) promoter transcription is activated by Pax5 through its recruitment of Ets family proteins to a composite site, the P5-EBS (Pax5-Ets binding site). Previously, X-ray crystallographic analys...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2009
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2763353/ https://ncbi.nlm.nih.gov/pubmed/19616560 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2009.07.028 |
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