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Wnt2/2b and β-catenin signaling are necessary and sufficient to specify lung progenitors in the foregut

The primitive foregut is patterned in a manner that spatially promotes proper organ specification along the anterior-posterior foregut axis. However, the molecular pathways that specify foregut endoderm progenitors are poorly understood. We show that Wnt2/2b signaling is required to specify lung end...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Goss, Ashley M., Tian, Ying, Tsukiyama, Tadasuke, Cohen, Ethan David, Zhou, Diane, Lu, Min Min, Yamaguchi, Terry P., Morrisey, Edward E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2763331/
https://ncbi.nlm.nih.gov/pubmed/19686689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2009.06.005
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