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A Mechanistic Latent Variable Model for Estimating Drug Concentrations in the Male Genital Tract: A Case Study in Drug Kinetics

The purpose of this study is to develop statistical methodology to facilitate indirect estimation of the concentration of antiretroviral drugs and viral loads in the prostate gland and the seminal vesicle. The differences in antiretroviral drug concentrations in these organs may lead to suboptimal c...

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Detalhes bibliográficos
Main Authors: Choi, Leena, Caffo, Brian, Rohde, Charles, Ndovi, Themba T., Hendrix, Craig W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2763330/
https://ncbi.nlm.nih.gov/pubmed/17948921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/sim.3097
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